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Propyl Paraben Sodium I.P


SYSTEM MANUAL
ISSUE NO : 01
Document No.
Revision No.
Effective date
Page
QAI/Q/03/22
05
05-Sept-08
1 of 1
PROPYL PARABEN  SODIUM I.P.
 Chemical Name

Sodium Propyl 4-Hydroxybenzoate

 Molecular Formula

C10H11NaO3

 Molecular Weight

202.18

 Structural Formula
 CAS Number

35285-69-9

 Packing

25 Kg, 20kg(4 x 5 kg)

 The Shelf-life

3 years

 Storage conditions and  precautions

Store in a well-closed containers.

 Use Antimicrobial Preservative
 
NO.
Test
Observation
1.
 Description A white, crystalline powder, odourless or almost odourless; hygroscopic.
2.
 Solubility Freely soluble in water and in ethanol (50%), sparingly soluble in ethanol (95%), practically in soluble in fixed oils.
3.
 Identifiction

A. Dissolve 0.5 gm in 5 ml of water and acidify to litmus paper with hydrochloric acid; a white precipitate is produced. Wash the precipitate with water and dry. The infrared absorption spectrum of the precipitate, appendix 5.4 is concordant with the reference spectrum of Propyl Paraben or with the spectrum obtained from Propyl Paraben RS. 

B. The precipitate obtained in test A on ignition gives the reactions of sodium salts, appendix 3.1

4.
 PH Between 9.5 to 10.5, determined in a 0.1% w/v solution, appendix 8.11
5.
 Appearance of solution A 10% solution in water is clear, 10% solution in water is clear, or not more opalescence than Opalescence standard OS1 prepared by 5.0 ml of Opalescence standard & 95 ml of water .
6.
 Chlorides Not more than 330 ppm
7.
 Sulphate Not more than 0.12%
8.
 Water Not more than 5.0%
9.
 Assay on dried  basis (as  C10H11NaO3) Between 99.0% to 102.0%
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