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First identification: A, B.
Second identification: A, C, D.
A. Melts between 125°C and 128°C.
B.
The infrared absorption spectrum is
concordant with the reference spectrum of
methyl paraben or with the spectrum obtained
from methyl paraben CRS.
C.
Examine the chromatograms obtained in
the test for related substances. The
principle spot in the chromatogram obtained
with test solution (b) is similar in
position and size to the principle spot in
the chromatogram obtained with reference
solution (b).
D.
To
about 10 mg in a test tube add 1 ml of
sodium carbonate solution R, boil for 30
seconds and cool (solution A). To a further
10 mg in a test tube add 1 ml of sodium
carbonate solution R, the substance partly
dissolves (solution B). Add at the same
time to each of solutions A and B 5 ml of
aminopyrazolone solution and 1 ml of
potassium ferricyanide solution R and mix.
Solution B is yellow to orange brown.
Solution A is orange to Red, the colour is
clearly more intense than any similar colour
that may be obtained with solution B |
